Leydig Cell Function in Man
نویسندگان
چکیده
In humans, as in all mammalian males, Leydig cells are the main source of the androgenic hormone, testosterone, which is essential for male sexual differentiation, gamete production and maturation, and development of secondary sexual characteristics. In this chapter, the development, steroidogenic function, and regulation of human Leydig cells are summarized. Clinical aspects of androgen secretion and pathology related to Leydig cells are also reviewed. The information presented is based, in part, on studies conducted in laboratory animals because of the larger database available for these species.
منابع مشابه
Leydig cell tumors of the testis.
Leydig cell tumors represent approximately one to three percent of all testicular tumors. Whereas in experimental animals predisposing conditions include administration of chemical carcinogens, hormones and heavy metals, environmental or endogenous factors in man are presently unrecognized. Leydig cell tumors do not show preferential lateralization or tendency for bilaterality. The symptoms are...
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